Magnetic Resonance Imaging of Temperature Changes During Interstitial Microwave Heating: A Phantom Study
journal contributionposted on 21.05.2021, 15:55 by I. Alex Vitkin, J. A. Moriarty, R. D. Peters, Michael C. Kolios, A. S. Gladman, J. C. Chen, R. S. Hinks, J. W. Hunt, B. C. Wilson, A. C. Easty, M. J. Bronskill, W. Kucharczyk, Michael D. Sherar, R. M. Henkelman
Changes in magnetic resonance (MR) signals during interstitial microwave heating are reported, and correlated with simultaneously acquired temperature readings from three fiber-optic probes implanted in a polyacrylamide gel phantom. The heating by a MR-compatible microwave antenna did not interfere with simultaneous MR image data acquisition. MR phase-difference images were obtained using a fast two-dimensional-gradient echo sequence. From these images the temperature-sensitive resonant frequency of the1H nuclei was found to decrease approximately by 0.008 ppm/°C. The method and results presented here demonstrate that noninvasive MR-temperature imaging can be performed simultaneously with interstitial microwave thermal treatment.